Fly Brain HubFANC (Female Adult Nerve Cord)
Harvard Medical School (Wei-Chung Allen Lee lab)
GridTape-TEM volume of an adult female fruit fly's ventral nerve cord from the Lee lab at Harvard Medical School, with automated reconstruction and an ongoing community proofreading effort. The original EM dataset was described in Cell in 2021, and the connectomic reconstruction (Azevedo, Lesser, Phelps, Mark et al.) in Nature in 2024. This repository hosts the pip-installable fanc-fly Python package (GPL-3.0) and the project wiki, which fanc.community redirects to.
Sources checked
Every fact above was read from these pages on the date the entry was added.
- github.com https://github.com/htem/FANC_auto_recon
- github.com https://github.com/htem/FANC_auto_recon/wiki/
Used by: 3 projects
coconatfly
Gregory Jefferis (natverse)
An R package from Greg Jefferis that puts one uniform interface over the major fly connectomes so the same partner-query or cell-type comparison can be run across hemibrain, FlyWire, MANC, FANC, BANC, the male CNS and the male optic lobe. It is flagged as experimental and its API may still change, but it is already the workhorse for hemibrain-versus-FlyWire comparisons in the natverse community.
Virtual Fly Brain
Virtual Fly Brain consortium (UK institutions incl. MRC HGU)
A long-running UK-funded web atlas that registers neuron images, gene-expression patterns and connectomics onto standard Drosophila brain templates and links them through an anatomy ontology, so anatomy, expression and connectivity can be cross-searched in one place. Supported since 2009, it now indexes over 600,000 3D images and roughly 490,000 neurons with connectivity, spanning hemibrain, FlyWire, FANC and the larval L1EM data. The v2 front end (geppetto-vfb) is an MIT-licensed customisation of the Geppetto platform.
Wikipedia: Drosophila connectome
Wikipedia (Wikimedia Foundation)
Community-written encyclopedia article that serves as a one-stop overview of fruit fly connectomics, explaining why Drosophila is used as a model and walking through the major datasets from the 3,016-neuron larval brain to the adult hemibrain, FlyWire, the FANC and MANC nerve cords, and the 2025 whole-CNS BANC and male CNS reconstructions. It also touches on how wiring structure relates to behavior. Text is under CC BY-SA 4.0; last edited August 11, 2026.