What is a fly brain, and what can it do now?

The "fly brain" in these projects is a wiring diagram: a table of which neuron connects to which, and how many synapses lie between them. A wiring diagram does not run on its own.

A measured wiring diagram plus a chosen dynamical model makes a running fly brain MEASUREDWiring — which neuron, to which, how many+CHOSENDynamics — thresholds, time constants=A running "fly brain"
What runs is measured wiring plus a model somebody chose.

The measured part: wiring diagrams

The chosen part: what the wiring leaves out

Excitatory or inhibitory?
Inferred from neurotransmitter predictions
How strong is a synapse?
Most projects use the raw synapse count as the weight
Time constants, thresholds
Chosen per project, usually the Shiu et al. 2024 model

Machine learning decides weights by training. Here they are replaced by counts off a microscope. Are weights learned, or measured?

What it can and cannot do

Now possible

Still not possible

What arrived is not a mind. It is a shared testbed.

What gets listed here

Only what could be confirmed from the primary source is listed. Two things count for a lot: whether controls were run, and whether the failures were written down.Editorial policy / Submit a project

A note on numbers: projects using the same MaleCNS release quote 24.5 to 25.6 million synapses. They count different things, so check which release and which quantity a figure refers to.