Tools & Libraries

connectome_interpreter

Yijie Yin, University of Cambridge

A Python library that turns a wiring diagram into testable hypotheses about circuit function, and it runs on a laptop or in Colab even for whole-brain analyses of around 140,000 neurons. It computes polysynaptic effective connectivity between groups of neurons with or without signs, retrieves and plots the actual subcircuit between sources and targets, and exposes a differentiable connectome model. Installable from PyPI, with an accompanying preprint and Colab notebook.

Official site ↗Repository ↗

connectome_interpreter

#effective-connectivity#path-finding#differentiable#python#whole-brain

Sources checked

Every fact above was read from these pages on the date the entry was added.

  • github.com https://github.com/YijieYin/connectome_interpreter
  • biorxiv.org https://www.biorxiv.org/content/10.1101/2025.09.29.679410v2