Simulation & Emulation

Fly Connectome Research (hemibrain lesion study)

@alok-108

A lesion study rather than a demo. A 1,000-neuron subnetwork of the Janelia hemibrain, picked by highest total degree (113,089 directed edges), is run as a point LIF network, and then neurons are deleted to see what the dynamics need. Removing 10% of the hubs cuts recruited unstimulated neurons from 653 to 92, while deleting twice as many at random leaves 299 on average. A sweep of 157 runs varies drive fraction, coupling and timestep. The limitations section is blunt: every synapse is modelled as excitatory, so high coupling runs away, and the hub-enriched sample must not be generalised.

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Fly Connectome Research (hemibrain lesion study)

#hemibrain#virtual-lesion#hub-neurons#lif#sensitivity-analysis

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