FlyLite

Asks how sparse a fly-brain model can get before it stops working. Starting from the 127,400 neurons and 14.7 million weighted edges of the validated whole-brain model, it removes edges with six different operators at the same edge budget, keeping magnitude, wiring position or neither, including a task-aware one, and then re-runs three experimentally validated circuits in both a silent and a spontaneously active network. Hypotheses were fixed before the first phase. Everything runs on a laptop processor or a free cloud runtime, at roughly one to three minutes per simulated second.

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