PoopFly

A whole-MaleCNS spiking fly that decides for itself when to defecate. It eats, builds up gut pressure, senses that pressure through interoceptive neurons, and the action is read out of motor-population firing rates rather than compared against a threshold. Relief lowers the pressure and produces a dopamine-like homeostatic reward driving three-factor plasticity, so the fly gets quicker at relieving itself when full and settles on a preferred background song. The run shown uses a 100,000-neuron subset with 19,716,276 synapses, computed in a Web Worker in the browser.

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#interoception#homeostatic-reward#three-factor-plasticity#browser#web-worker#malecns