A fruit fly connectome that learns

Runs the classic punished-odour experiment on the male-cns v1.0 mushroom body and adds the controls that say whether the learning is real. Across five odour pairs, 200 flies each, avoidance of the punished odour rises from about 45% to 70-80% over 15 trials; punishment with no odour stays near chance, and shuffled wiring never learns because the punishment dopamine neuron reaches 409 Kenyon cells in the real graph but only 10 after shuffling. It also reports why the whole-brain model cannot learn this: two odours light up nearly the same Kenyon cells, 99% overlap at default inhibition.

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#malecns#mushroom-body#associative-learning#shuffled-control#negative-results